Podcast | Can AI Be Your Nutritionist? GLP-1s and Weight Health with Ashley Koff

Oct 22, 2026

Or listen on Spotify. 


Every bad thing you’ve heard about GLP-1s may be true, and so is everything you’ve been told about calories in, calories out. Ashley Koff says both miss the real problem.

 Jeff sits down with Ashley Koff, RD, a registered dietitian and author of Your Best Shot, to talk about GLP-1s, weight health, and whether AI can ever be as curious as a good practitioner. Jeff shares what happened when he started low-dose tirzepatide and his appetite disappeared overnight.

  • Why "weight loss" can include bone, muscle, hair and testosterone, and what Ashley measures instead
  • The first two days after a weekly shot: why she moves fiber later in the week and leans on soups and smoothies
  • Why feeling no hunger at all on a GLP-1 can be a sign the dose is wrong
  • Why calories are "only potential energy" until digestion turns them into something usable
  • How Jeff used AI to keep five specialists on the same page for his father, and why Ashley built her own AI nutritionist

This episode is for anyone who started a GLP-1 and can barely eat, or who's getting textbook nutrition answers that don't fit their body. Ashley's book Your Best Shot is available now.

 

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About the Commune Podcast

Hosted by Jeff Krasno, the Commune podcast features thoughtful conversations for modern times. Not always comfortable but definitely needed, we explore both humanity and our human-ness. How can we live healthy, purpose-filled lives and be in service of something bigger? Guests include spiritual teachers, poets, scientists, philosophers, and activists for food sustainability, functional medicine, mental and physical health, and collective healing.

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